Retatrutide 20mg
£200.00
Pound sterling (£) - GBP
Retatrutide 20mg
Retatrutide is an investigational drug,
according to justmelt.com. It is a novel triple agonist for glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide 1 (GLP-1), and glucagon (GCG) receptors. It is being studied for its potential in treating obesity and managing weight loss.Â
How it works
Retatrutide targets three key receptors involved in metabolic regulation:Â
- GLP-1 receptors:Â Regulate blood sugar by stimulating insulin secretion and slowing gastric emptying, leading to improved glycemic control and reduced appetite.
- GIP receptors: Enhance insulin secretion in a glucose-dependent manner and may improve insulin sensitivity, according to canadianinsulin.com.
- Glucagon receptors:Â Mobilize stored energy and increase metabolism, aiding in weight loss and overall metabolic improvement.Â
This multi-faceted approach aims to improve glucose homeostasis, enhance satiety, and increase energy expenditure.Â
Dosage and administration
Retatrutide is administered via subcutaneous injection, typically using a pre-filled pen. The appropriate dosage for individuals is determined by a healthcare provider based on their specific needs and treatment goals. Clinical trials have explored different dosages.Â
Clinical trial results
Phase 2 clinical trial results for Retatrutide in weight loss have been published in The New England Journal of Medicine. Participants in the study experienced significant weight reduction. The trial also showed improvements in cardiometabolic markers such as blood pressure, lipids, and liver fat.Â
Side effects
Common side effects linked to Retatrutide are primarily gastrointestinal, including nausea, vomiting, diarrhea, and constipation. These effects are often mild to moderate and may lessen as the body adjusts to the medication. Some individuals might experience a temporary increase in heart rate. Less frequent but potentially serious side effects can include pancreatitis and issues with the gallbladder. Monitoring side effects and discussing them with a healthcare professional is important.Â
Availability
Retatrutide is currently undergoing clinical trials and has not received FDA approval for any use. It is for investigational use only and is not available for prescription or retail sale. Phase 3 clinical trials are ongoing.Â
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